Skin Cancer & You

Lupus Research Institute-funded researcher Betty Tsao, PhD, at the University of California Los Angeles has discovered that humans - males in particular - with a variant form of the immune receptor gene "Toll Like Receptor 7 (TLR7)" are at increased risk of developing the autoimmune disease systemic lupus erythematosus (lupus). This breakthrough finding offers renewed hope for developing more targeted treatments...

Sociologist Ms Lucía Merino presented her PhD thesis entitled, Digital natives: a study of the technological socialisation of young people, at the University of the Basque Country (UPV/EHU). Considering that young people nowadays are natives of the so-called digital culture, Ms Merino explored their relationship with the new technologies and how they learn and socialise through them. With this research, the author wished to set out guidelines as a basis to continue studying the so-called digital natives in the future...

The results of a three-year research project into pandemic flu preparedness in Europe will be launched at a meeting in Brussels in September. The results of the PHLawFlu (Public Health Law Flu) conference, Pandemic Influenza Preparedness in Europe: Are National Public Health Laws Fit for Purpose? will be presented by Professor Richard Coker, Professor of Public Health at the London School of Hygiene & Tropical Medicine (LSHTM) on 23 September at the European Parliament in Brussels...

Judith Kulich, Associate Principal, and Emily Jin, Manager, at ZS Associates talk to eyeforpharma about how patient flow modeling can inform forecasting. Patient flow, or system dynamics forecasting is a common approach for modeling situations in which patient potential is affected by movement between disease states. The technique is used frequently in oncology, diabetes, RA, and other markets with lines of therapy dynamics...

A basic requirement for growth and life of a multicellular organism is the ability of its cells to divide. Chromosomes in the cells duplicate and are then distributed among the daughter cells. This distribution is organized by a protein complex made up of several hundred different proteins, called the centrosome. In cancer cells, the centrosome often assumes an unnatural shape or is present in uncontrolled numbers. The reasons for this were previously largely unknown...

Researchers from across the U.S., as part of the Infantile Spasms Working Group (ISWG), established guidelines for the diagnosis and treatment of infantile spasms (IS). The goal of the ISWG is to improve patient outcomes by creating protocols that educate pediatricians on early diagnosis and treatment options. Full details of this study appear online in Epilepsia, a journal published by Wiley-Blackwell on behalf of the International League Against Epilepsy. Infantile spasms-known also as West syndrome and named after Dr...

Cincinnati, OH, September 2, 2010 The existence of chronic Lyme disease is an issue of sharp debate within the medical community. Some health care workers who call themselves "Lyme literate" insist that chronic Lyme disease is frequently diagnosed and treated by primary care physicians. Others, however, including the American Academy of Pediatrics and the Infectious Diseases Society of America, state that there is no convincing biological evidence that chronic Lyme disease exists...

The majority of rare diseases are hereditary. But despite significant progress in genome research, in most cases their exact cause remains unclear. The discovery of the underlying genetic defect is, however, a prerequisite for their definitive diagnosis and the development of innovative approaches to their treatment. Scientists at the Max Planck Institute for Molecular Genetics and the Institute of Medical Genetics at the Charité Universitätsmedizin Berlin have succeeded in using a new process with which all of the genes in the human genome can be analysed simultaneously...

A large international study aimed at improving the care of muscular dystrophy patients worldwide is being launched by physicians, physical therapists, and researchers at the University of Rochester Medical Center. Neurologist Robert "Berch" Griggs, M.D., is heading the study of treatments for Duchenne muscular dystrophy, the most common form of the disease that affects children. The condition, which affects boys almost exclusively, progresses rapidly. Boys' symptoms start when they are toddlers; untreated, they end up in a wheelchair before they become teenagers...

The Medical Affairs function arguably plays the most critical role in a biopharmaceutical organization, with heavy responsibilities across areas such as clinical development, scientific publications, KOL development, and medical education. These areas must operate effectively for new products to succeed. Appropriate spending across these activities is one of the challenges facing the Medical Affairs function as it attempts to balance its different roles across the organization...